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Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, v.v.i.

Description and mission

The Institute carries out fundamental research in organic chemistry, biochemistry and related disciplines, focusing in particular on medical and environmental applications. The mission of the Institute is independent basic research (with the purpose to collect new knowledge) in organic chemistry and biochemistry, and molecular oriented disciplines related to organic chemistry and biochemistry, with strong emphasis on the application of the results in practice.

Research Areas

  • Bioorganic and Medicinal Chemistry
  • Biochemistry and Molecular Biology
  • Organic Synthesis
  • Chemistry of Natural Products
  • Spectroscopy and Physical Organic Chemistry
  • Computational Chemistry

Excellence in research leads to excellence in technology transfer

Over almost 60 years of the existence of the institute, there have been numerous projects successfully transferred from basic research into commercial practice. An example is given in the figure below which includes also the most successful discovery of novel antiviral drugs coming from the laboratory of prof. Antonín Holý and developed by long term partner – US biotech company Gilead Sciences.

Interest to collaborate

There is continuous development of new molecules, new approaches in many fields of research at the institute and we are happy to establish new collaborations with commercial partners. The tech-transfer is organized through our daughter company IOCB TTO s.r.o., or

The Project is co-financed by the European Regional Development Fund and Czech Ministry of Industry and Trade